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Symbol Name ID |
Ptpn11
protein tyrosine phosphatase, non-receptor type 11 MGI:99511 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatomegaly |
| Disease(s) Associated with PTPN11 | |
| Noonan syndrome |
| Mouse Phenotypes | abnormal liver sinusoid morphology |
hepatic necrosis |
focal hepatic necrosis |
increased hepatocyte proliferation |
enlarged liver |
liver hyperplasia |
increased liver glycogen level |
decreased liver triglyceride level |
increased liver triglyceride level |
liver inflammation |
abnormal liver morphology |
abnormal liver parenchyma morphology |
abnormal hepatocyte morphology |
small liver |
hepatic steatosis |
liver fibrosis |
increased liver adenoma incidence |
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| Availability | Mouse Genotype | |||||||||||||||||
| Ptpn11tm1Bgn/Ptpn11tm1Bgn | ||||||||||||||||||
| Ptpn11tm1.1Ics/Ptpn11+ | ||||||||||||||||||
| Ptpn11tm1Bgn/Ptpn11+ | ||||||||||||||||||
| Ptpn11tm1Gsf/Ptpn11tm1Gsf Tg(Camk2a-cre)2Szi/0 (conditional) |
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| Ptpn11tm1Gsf/Ptpn11tm1Gsf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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| Ptpn11tm1Ckq/Ptpn11+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Ptpn11tm6Bgn/Ptpn11+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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